This report is organized as follows. Section 2 presents the results of comprehensive two-dimensional and full three-dimensional models to analyze thermal, hydrological, and mechanical effects of Options 2 and 3, which were formerly evaluated using simple one- and two-dimensional models. Impacts on the spatial and temporal redistribution of water vapor and condensed water are evaluated, with particular emphasis on how liquid water, initially driven away by radiogenic heating, eventually condenses and drains around but not through the emplacement tunnels. Possible coupling among thermal, hydrological, and mechanical processes during the initial thermal heating period are also analyzed. Section 3 explores the engineering feasibility of constructing multiple emplacement drifts for Options 2 and 3, with a discussion of impacts on ventilation. The potential impacts on long-term safety from positioning multiple emplacement drifts within the existing disposal blocks at Yucca Mountain are discussed in Section 4. A preliminary cost analysis is presented in Section 5 to provide an initial basis for comparing expanded capacity options with other waste management approaches. Section 6 provides a summary of results and recommendations based on the reported analyses.